Cyclohexanone is typically synthesised from phenol or cyclohexane. The phenol route consists of two stages. In the first stage, phenol and hydrogen react at around 180°C in the presence of a nickel catalyst to form cyclohexanol. This hydrogenation stage is followed by a dehydrogenation stage in which the cyclohexanol is reacted in the gaseous phase with a copper catalyst at around 400°C to yield the cyclohexanone. The alternative route involves the air oxidation of cyclohexane, which results in the production of KA oil, a mixture of cyclohexanol and cyclohexanone. In 1974, a massive explosion occurred in the cyclohexane oxidation section of Nypro Ltd's Caprolactam plant in Flixborough, England. Source Link- https://coherentmarketinsightsus.blogspot.com/2022/08/in-organic-chemistry-caprolactam-cpl.html
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